FEZ1

GENE INFORMATION

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Gene name

FEZ1

Synonyms

Description

Fasciculation and elongation protein zeta 1 (zygin I) (HGNC Symbol)

Entrez gene summary

This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q24.2

Chromosome location (bp)

125315646 - 125366213

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000149557 (version 75.37)

Entrez gene

9638

UniProt

Q99689 (UniProt - Evidence at protein level)

neXtProt

NX_Q99689

Antibodypedia

FEZ1 antibodies
 

PROTEIN VIEW

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FEZ1-001
 
FEZ1-004
 
FEZ1-005
 
FEZ1-006
 
FEZ1-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FEZ1-001 ENSP00000278919
ENST00000278919
Q99689
Show all »
Show » Show » 392 45.1 No 0
FEZ1-004 ENSP00000434803
ENST00000527534
E9PNH2
Show all »
Show » Show » 79 9.1 No 0
FEZ1-005 ENSP00000431521
ENST00000524435
Q99689
Show all »
Show » Show » 104 12.1 No 0
FEZ1-006 ENSP00000393425
ENST00000366139
Q99689
Show all »
Show » Show » 104 12.1 No 0
FEZ1-017 ENSP00000463116
ENST00000577924
Show » 207 23.7 No 0