FREM2

GENE INFORMATION

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Gene name

FREM2 (HGNC Symbol)

Synonyms

DKFZp686J0811

Description

FRAS1 related extracellular matrix protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]

Chromosome

13

Cytoband

q13.3

Chromosome location (bp)

39261266 - 39460074

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150893 (version 75.37)

Entrez gene

341640

UniProt

Q5SZK8 (UniProt - Evidence at protein level)

neXtProt

NX_Q5SZK8

Antibodypedia

FREM2 antibodies
 

PROTEIN VIEW

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FREM2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FREM2-001 ENSP00000280481
ENST00000280481
Q5SZK8
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