CCL28

GENE INFORMATION

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Gene name

CCL28 (HGNC Symbol)

Synonyms

CCK1, MEC, SCYA28

Description

Chemokine (C-C motif) ligand 28 (HGNC Symbol)

Entrez gene summary

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Chromosome

5

Cytoband

p12

Chromosome location (bp)

43376747 - 43412493

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151882 (version 75.37)

Entrez gene

56477

UniProt

Q9NRJ3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRJ3

Antibodypedia

CCL28 antibodies
 

PROTEIN VIEW

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CCL28-001
 
CCL28-002
 
CCL28-003
 
CCL28-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL28-001 ENSP00000426424
ENST00000489442
Q9NRJ3
Show all »
Show » Show » 127 14.3 Yes 0
CCL28-002 ENSP00000354416
ENST00000361115
Q9NRJ3
Show all »
Show » Show » 127 14.3 Yes 0
CCL28-003 ENSP00000422369
ENST00000513525
D6RC73
Show all »
Show » Show » 80 9.3 No 0
CCL28-201 ENSP00000443823
ENST00000537013
Q9NRJ3
Show all »
Show » Show » 117 12.4 Yes 0