KCNE4

GENE INFORMATION

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Gene name

KCNE4 (HGNC Symbol)

Synonyms

MiRP3

Description

Potassium voltage-gated channel, Isk-related family, member 4 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q36.1

Chromosome location (bp)

223916532 - 224063117

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000152049 (version 75.37)

Entrez gene

23704

UniProt

Q8WWG9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WWG9

Antibodypedia

KCNE4 antibodies
 

PROTEIN VIEW

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KCNE4-001
 
KCNE4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNE4-001 ENSP00000281830
ENST00000281830
A5H1P5
Show all »
Show » Show » 221 23.8 No 1
KCNE4-201 ENSP00000473755
ENST00000604125
Q8WWG9
Show all »
Show » Show » 170 18.4 No 1