CENPH

GENE INFORMATION

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Gene name

CENPH

Synonyms

Description

Centromere protein H (HGNC Symbol)

Entrez gene summary

Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q13.2

Chromosome location (bp)

68485375 - 68506184

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153044 (version 75.37)

Entrez gene

64946

UniProt

Q9H3R5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H3R5

Antibodypedia

CENPH antibodies
 

PROTEIN VIEW

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CENPH-001
 
CENPH-002
 
CENPH-003
 
CENPH-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CENPH-001 ENSP00000283006
ENST00000283006
Q9H3R5
Show all »
Show » Show » 247 28.5 No 0
CENPH-002 ENSP00000426014
ENST00000515001
B3KVZ3
Show all »
Show » Show » 228 26.2 No 0
CENPH-003 ENSP00000423936
ENST00000502689
Show » Show » 187 22 No 0
CENPH-004 ENSP00000422665
ENST00000513575
D6RBJ6
Show all »
Show » 98 10.9 No 0