CETN3

GENE INFORMATION

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Gene name

CETN3 (HGNC Symbol)

Synonyms

CEN3

Description

Centrin, EF-hand protein, 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Chromosome

5

Cytoband

q14.3

Chromosome location (bp)

89688078 - 89705603

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153140 (version 75.37)

Entrez gene

1070

UniProt

O15182 (UniProt - Evidence at transcript level)

neXtProt

NX_O15182

Antibodypedia

CETN3 antibodies
 

PROTEIN VIEW

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CETN3-001
 
CETN3-002
 
CETN3-003
 
CETN3-004
 
CETN3-005
 
CETN3-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CETN3-001 ENSP00000283122
ENST00000283122
O15182
Show all »
Show » Show » 167 19.5 No 0
CETN3-002 ENSP00000428259
ENST00000522083
E5RJF8
Show all »
Show » Show » 191 22.4 No 0
CETN3-003 ENSP00000430361
ENST00000522864
E5RFM2
Show all »
Show » Show » 153 18 No 0
CETN3-004 ENSP00000430409
ENST00000522565
E5RK82
Show all »
Show » Show » 156 18.3 No 0
CETN3-005 ENSP00000429875
ENST00000522842
E5RH67
Show all »
Show » Show » 111 12.9 No 0
CETN3-006 ENSP00000429772
ENST00000518458
H0YBL5
Show all »
Show » Show » 81 9.6 No 0