BMP6

GENE INFORMATION

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Gene name

BMP6 (HGNC Symbol)

Synonyms

VGR, VGR1

Description

Bone morphogenetic protein 6 (HGNC Symbol)

Entrez gene summary

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p24.3

Chromosome location (bp)

7727030 - 7881655

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153162 (version 75.37)

Entrez gene

654

UniProt

P22004 (UniProt - Evidence at protein level)

neXtProt

NX_P22004

Antibodypedia

BMP6 antibodies
 

PROTEIN VIEW

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BMP6-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BMP6-001 ENSP00000283147
ENST00000283147
P22004
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