PTPRD

GENE INFORMATION

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Gene name

PTPRD (HGNC Symbol)

Synonyms

HPTP, PTPD

Description

Protein tyrosine phosphatase, receptor type, D (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]

Chromosome

9

Cytoband

p23

Chromosome location (bp)

8314246 - 10612723

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153707 (version 75.37)

Entrez gene

5789

UniProt

P23468 (UniProt - Evidence at protein level)

neXtProt

NX_P23468

Antibodypedia

PTPRD antibodies
 

PROTEIN VIEW

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 « 
 
PTPRD-001
 
PTPRD-002
 
PTPRD-003
 
PTPRD-006
 
PTPRD-008
 
PTPRD-201
 
PTPRD-202
 
PTPRD-203
 
PTPRD-204
 
PTPRD-205
 
PTPRD-206
 
PTPRD-207
 
PTPRD-208
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTPRD-001 ENSP00000417661
ENST00000463477
C9J8S8
Show all »
Show » Show » 202 22.4 Yes 0
PTPRD-002 ENSP00000370593
ENST00000381196
P23468
Show all »
Show » Show » 1912 214.8 Yes 1
PTPRD-003 ENSP00000417093
ENST00000486161
P23468
Show all »
Show » Show » 1505 169.6 Yes 1
PTPRD-006 ENSP00000380731
ENST00000397606
P23468
Show all »
Show » Show » 1505 169.5 Yes 1
PTPRD-008 ENSP00000417890
ENST00000481079
C9J6E4
Show all »
Show » Show » 93 10.4 Yes 0
PTPRD-201 ENSP00000347373
ENST00000355233
P23468
Show all »
Show » Show » 1506 169.7 Yes 1
PTPRD-202 ENSP00000348812
ENST00000356435
P23468
Show all »
Show » Show » 1912 214.8 Yes 1
PTPRD-203 ENSP00000351293
ENST00000358503
G3XAD5
Show all »
Show » Show » 1890 212.2 Yes 1
PTPRD-204 ENSP00000353187
ENST00000360074
G3XAE2
Show all »
Show » Show » 1899 213.3 Yes 1
PTPRD-205 ENSP00000380735
ENST00000397611
F5GWT7
Show all »
Show » Show » 1502 169.3 Yes 1
PTPRD-206 ENSP00000380741
ENST00000397617
F5GWR7
Show all »
Show » Show » 1505 169.4 Yes 1
PTPRD-207 ENSP00000440515
ENST00000537002
F5GWY7
Show all »
Show » Show » 1502 169.5 Yes 1
PTPRD-208 ENSP00000438164
ENST00000540109
P23468
Show all »
Show » Show » 1912 214.8 Yes 1