FAM134B

GENE INFORMATION

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Gene name

FAM134B (HGNC Symbol)

Synonyms

FLJ20152

Description

Family with sequence similarity 134, member B (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Chromosome

5

Cytoband

p15.1

Chromosome location (bp)

16473147 - 16617167

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154153 (version 75.37)

Entrez gene

54463

UniProt

Q9H6L5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H6L5

Antibodypedia

FAM134B antibodies
 

PROTEIN VIEW

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FAM134B-001
 
FAM134B-003
 
FAM134B-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM134B-001 ENSP00000304642
ENST00000306320
Q9H6L5
Show all »
Show » Show » 497 54.7 No 2
FAM134B-003 ENSP00000382691
ENST00000399793
Q9H6L5
Show all »
Show » Show » 356 39.3 No 1
FAM134B-005 ENSP00000425089
ENST00000510362
Show » 217 23.4 No 0