PDLIM3

GENE INFORMATION

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Gene name

PDLIM3 (HGNC Symbol)

Synonyms

ALP

Description

PDZ and LIM domain 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]

Chromosome

4

Cytoband

q35.1

Chromosome location (bp)

186422851 - 186456766

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154553 (version 75.37)

Entrez gene

27295

UniProt

Q53GG5 (UniProt - Evidence at protein level)

neXtProt

NX_Q53GG5

Antibodypedia

PDLIM3 antibodies
 

PROTEIN VIEW

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PDLIM3-001
 
PDLIM3-002
 
PDLIM3-005
 
PDLIM3-006
 
PDLIM3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDLIM3-001 ENSP00000284770
ENST00000284770
Q53GG5
Show all »
Show » Show » 364 39.2 No 0
PDLIM3-002 ENSP00000284771
ENST00000284771
Q53GG5
Show all »
Show » Show » 316 34.3 No 0
PDLIM3-005 ENSP00000421972
ENST00000512293
D6RAF1
Show all »
Show » 42 4.5 No 0
PDLIM3-006 ENSP00000425138
ENST00000505886
D6RAF1
Show all »
Show » 42 4.5 No 0
PDLIM3-201 ENSP00000284767
ENST00000284767
Q53GG5
Show all »
Show » Show » 189 20.2 No 0