NAT2

GENE INFORMATION

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Gene name

NAT2 (HGNC Symbol)

Synonyms

AAC2

Description

N-acetyltransferase 2 (arylamine N-acetyltransferase) (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p22

Chromosome location (bp)

18248755 - 18258728

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156006 (version 75.37)

Entrez gene

10

UniProt

P11245 (UniProt - Evidence at protein level)

neXtProt

NX_P11245

Antibodypedia

NAT2 antibodies
 

PROTEIN VIEW

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NAT2-001
 
NAT2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NAT2-001 ENSP00000286479
ENST00000286479
P11245
Show all »
Show » Show » 290 33.6 No 0
NAT2-002 ENSP00000428416
ENST00000520116
E7EWF9
Show all »
Show » Show » 160 18.8 No 0