WIPI2

GENE INFORMATION

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Gene name

WIPI2 (HGNC Symbol)

Synonyms

ATG18B, Atg21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984

Description

WD repeat domain, phosphoinositide interacting 2 (HGNC Symbol)

Entrez gene summary

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]

Chromosome

7

Cytoband

p22.1

Chromosome location (bp)

5229819 - 5273457

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000157954 (version 75.37)

Entrez gene

26100

UniProt

Q9Y4P8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4P8

Antibodypedia

WIPI2 antibodies
 

PROTEIN VIEW

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WIPI2-001
 
WIPI2-002
 
WIPI2-005
 
WIPI2-007
 
WIPI2-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WIPI2-001 ENSP00000288828
ENST00000288828
Q9Y4P8
Show all »
Show » Show » 454 49.4 No 0
WIPI2-002 ENSP00000384945
ENST00000401525
Q9Y4P8
Show all »
Show » Show » 436 47.5 No 0
WIPI2-005 ENSP00000429654
ENST00000484262
Q9Y4P8
Show all »
Show » Show » 384 42.1 No 0
WIPI2-007 ENSP00000371821
ENST00000382384
Q9Y4P8
Show all »
Show » Show » 425 46.4 No 0
WIPI2-008 ENSP00000385297
ENST00000404704
Q9Y4P8
Show all »
Show » Show » 443 48.2 No 0