CDA

GENE INFORMATION

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Gene name

CDA (HGNC Symbol)

Synonyms

CDD

Description

Cytidine deaminase (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.12

Chromosome location (bp)

20915441 - 20945401

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158825 (version 75.37)

Entrez gene

978

UniProt

P32320 (UniProt - Evidence at protein level)

neXtProt

NX_P32320

Antibodypedia

CDA antibodies
 

PROTEIN VIEW

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CDA-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDA-001 ENSP00000364212
ENST00000375071
P32320
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