TFF2

GENE INFORMATION

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Gene name

TFF2 (HGNC Symbol)

Synonyms

SML1

Description

Trefoil factor 2 (HGNC Symbol)

Entrez gene summary

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.3

Chromosome location (bp)

43766466 - 43771237

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160181 (version 75.37)

Entrez gene

7032

UniProt

Q03403 (UniProt - Evidence at protein level)

neXtProt

NX_Q03403

Antibodypedia

TFF2 antibodies
 

PROTEIN VIEW

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TFF2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TFF2-001 ENSP00000291526
ENST00000291526
Q03403
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