CYP11B1

GENE INFORMATION

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Gene name

CYP11B1 (HGNC Symbol)

Synonyms

CPN1, CYP11B, FHI, P450C11

Description

Cytochrome P450, family 11, subfamily B, polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

143953772 - 143961262

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160882 (version 75.37)

Entrez gene

1584

UniProt

P15538 (UniProt - Evidence at protein level)

neXtProt

NX_P15538

Antibodypedia

CYP11B1 antibodies
 

PROTEIN VIEW

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CYP11B1-001
 
CYP11B1-002
 
CYP11B1-003
 
CYP11B1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP11B1-001 ENSP00000292427
ENST00000292427
P15538
Show all »
Show » Show » 503 57.6 No 0
CYP11B1-002 ENSP00000428043
ENST00000517471
P15538
Show all »
Show » Show » 437 49.7 No 0
CYP11B1-003 ENSP00000366903
ENST00000377675
Q4VAR0
Show all »
Show » Show » 574 65.1 No 0
CYP11B1-005 ENSP00000430144
ENST00000519285
H0YBR4
Show all »
Show » Show » 181 20.5 No 0