PTGER1

GENE INFORMATION

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Gene name

PTGER1 (HGNC Symbol)

Synonyms

EP1

Description

Prostaglandin E receptor 1 (subtype EP1), 42kDa (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

14583278 - 14586174

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000160951 (version 75.37)

Entrez gene

5731

UniProt

P34995 (UniProt - Evidence at transcript level)

neXtProt

NX_P34995

Antibodypedia

PTGER1 antibodies
 

PROTEIN VIEW

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PTGER1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTGER1-001 ENSP00000292513
ENST00000292513
P34995
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