CCL16

GENE INFORMATION

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Gene name

CCL16 (HGNC Symbol)

Synonyms

CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4

Description

Chemokine (C-C motif) ligand 16 (HGNC Symbol)

Entrez gene summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

34303529 - 34308532

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000161573 (version 75.37)

Entrez gene

6360

UniProt

O15467 (UniProt - Evidence at protein level)

neXtProt

NX_O15467

Antibodypedia

CCL16 antibodies
 

PROTEIN VIEW

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CCL16-001
 
CCL16-002
 
CCL16-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL16-001 ENSP00000293275
ENST00000293275
O15467
Show all »
Show » Show » 120 13.6 Yes 0
CCL16-002 ENSP00000431339
ENST00000483259
Show » Show » 95 10.8 No 0
CCL16-004 ENSP00000466279
ENST00000586567
K7ELY7
Show all »
Show » 53 5.7 Yes 0