GABRB1

GENE INFORMATION

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Gene name

GABRB1

Synonyms

Description

Gamma-aminobutyric acid (GABA) A receptor, beta 1 (HGNC Symbol)

Entrez gene summary

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

p12

Chromosome location (bp)

46995740 - 47428461

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163288 (version 75.37)

Entrez gene

2560

UniProt

P18505 (UniProt - Evidence at transcript level)

neXtProt

NX_P18505

Antibodypedia

GABRB1 antibodies
 

PROTEIN VIEW

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GABRB1-001
 
GABRB1-003
 
GABRB1-005
 
GABRB1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GABRB1-001 ENSP00000295454
ENST00000295454
P18505
Show all »
Show » Show » 474 54.2 Yes 4
GABRB1-003 ENSP00000426766
ENST00000510909
D6REL3
Show all »
Show » Show » 87 10.2 Yes 0
GABRB1-005 ENSP00000426753
ENST00000513567
D6REM0
Show all »
Show » Show » 117 13.5 No 0
GABRB1-201 ENSP00000440330
ENST00000538619
F5GXV5
Show all »
Show » Show » 404 46.4 No 4