ICOS

GENE INFORMATION

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Gene name

ICOS (HGNC Symbol)

Synonyms

AILIM, CD278

Description

Inducible T-cell co-stimulator (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q33.2

Chromosome location (bp)

204801471 - 204826300

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163600 (version 75.37)

Entrez gene

29851

UniProt

Q9Y6W8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6W8

Antibodypedia

ICOS antibodies
 

PROTEIN VIEW

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ICOS-001
 
ICOS-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ICOS-001 ENSP00000319476
ENST00000316386
Q9Y6W8
Show all »
Show » Show » 199 22.6 Yes 1
ICOS-002 ENSP00000415951
ENST00000435193
Q9Y6W8
Show all »
Show » Show » 168 19.1 Yes 1