DNASE1L3

GENE INFORMATION

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Gene name

DNASE1L3 (HGNC Symbol)

Synonyms

DNAS1L3, LSD

Description

Deoxyribonuclease I-like 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Chromosome

3

Cytoband

p14.3

Chromosome location (bp)

58177984 - 58200424

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163687 (version 75.37)

Entrez gene

1776

UniProt

Q13609 (UniProt - Evidence at protein level)

neXtProt

NX_Q13609

Antibodypedia

DNASE1L3 antibodies
 

PROTEIN VIEW

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DNASE1L3-001
 
DNASE1L3-002
 
DNASE1L3-003
 
DNASE1L3-005
 
DNASE1L3-006
 
DNASE1L3-007
 
DNASE1L3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNASE1L3-001 ENSP00000378053
ENST00000394549
Q13609
Show all »
Show » Show » 305 35.5 Yes 0
DNASE1L3-002 ENSP00000417047
ENST00000483681
C9J9N0
Show all »
Show » Show » 288 33.6 Yes 0
DNASE1L3-003 ENSP00000418509
ENST00000460422
C9J0L2
Show all »
Show » Show » 100 11.6 Yes 0
DNASE1L3-005 ENSP00000419052
ENST00000486455
Q13609
Show all »
Show » Show » 275 31.9 Yes 0
DNASE1L3-006 ENSP00000417976
ENST00000477209
H7C4R7
Show all »
Show » Show » 137 15.8 No 0
DNASE1L3-007 ENSP00000418113
ENST00000461914
C9J9N0
Show all »
Show » Show » 158 18.5 Yes 0
DNASE1L3-201 ENSP00000316193
ENST00000318316
Q13609
Show all »
Show » Show » 305 35.5 Yes 0