CXCL1

GENE INFORMATION

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Gene name

CXCL1 (HGNC Symbol)

Synonyms

FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1

Description

Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (HGNC Symbol)

Entrez gene summary

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]

Chromosome

4

Cytoband

q13.3

Chromosome location (bp)

74735110 - 74736959

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163739 (version 75.37)

Entrez gene

2919

UniProt

P09341 (UniProt - Evidence at protein level)

neXtProt

NX_P09341

Antibodypedia

CXCL1 antibodies
 

PROTEIN VIEW

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CXCL1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CXCL1-001 ENSP00000379110
ENST00000395761
P09341
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