METAP1

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SUBCELL ATLAS - HUMAN

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Summary

Mainly localized to the nucleus but excluded from the nucleoli. In addition localized to the cytoplasm or vesicles. Localized to the nucleus in mouse cells.

Main location

Nucleus but not nucleoli

Additional location

Cytoplasm, Vesicles

Reliability

Supportive

Protein evidence

Evidence at protein level

Assay summary

Analysis based on three antibodies, CAB025485, HPA037997 and HPA037998, using immunofluorescence in human and mouse cells
 

 

 

 

 

 

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HPA037997
HPA037997: U-2 OS
HPA037997: U-2 OS
Cell line: U-2 OS
Location: Nucleus but not nucleoli, Vesicles
Literature validation: Uncertain
HPA037997: A-431
HPA037997: A-431
Cell line: A-431
Location: Nucleus but not nucleoli, Vesicles
Literature validation: Uncertain
HPA037997: U-251 MG
HPA037997: U-251 MG
Cell line: U-251 MG
Location: Nucleus but not nucleoli, Vesicles
Literature validation: Uncertain
HPA037998
HPA037998: U-2 OS
HPA037998: U-2 OS
Cell line: U-2 OS
Location: Nucleus, Cytoplasm
Literature validation: Supportive
HPA037998: A-431
HPA037998: A-431
Cell line: A-431
Location: Nucleus
Literature validation: Supportive
HPA037998 stained U-251 MG
cells unspecifically
CAB025485
CAB025485: U-2 OS
CAB025485: U-2 OS
Cell line: U-2 OS
Location: Nucleus but not nucleoli, Cytoplasm
Literature validation: Supportive
CAB025485: A-431
CAB025485: A-431
Cell line: A-431
Location: Plasma membrane, Cytoplasm
Literature validation: Supportive
CAB025485: U-251 MG
CAB025485: U-251 MG
Cell line: U-251 MG
Location: Nucleus but not nucleoli, Cytoplasm
Literature validation: Supportive