HPGD

GENE INFORMATION

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Gene name

HPGD (HGNC Symbol)

Synonyms

SDR36C1

Description

Hydroxyprostaglandin dehydrogenase 15-(NAD) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Chromosome

4

Cytoband

q34.1

Chromosome location (bp)

175411328 - 175444305

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164120 (version 75.37)

Entrez gene

3248

UniProt

P15428 (UniProt - Evidence at protein level)

neXtProt

NX_P15428

Antibodypedia

HPGD antibodies
 

PROTEIN VIEW

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 « 
 
HPGD-001
 
HPGD-002
 
HPGD-003
 
HPGD-004
 
HPGD-005
 
HPGD-008
 
HPGD-010
 
HPGD-011
 
HPGD-013
 
HPGD-201
 
HPGD-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HPGD-001 ENSP00000296522
ENST00000296522
P15428
Show all »
Show » Show » 266 29 No 0
HPGD-002 ENSP00000422418
ENST00000510901
P15428
Show all »
Show » Show » 145 15.7 No 0
HPGD-003 ENSP00000425741
ENST00000508330
E9PD69
Show all »
Show » Show » 87 9.6 No 0
HPGD-004 ENSP00000420892
ENST00000504433
E9PBZ2
Show all »
Show » Show » 176 19.1 No 0
HPGD-005 ENSP00000427699
ENST00000510835
D6RHF8
Show all »
Show » Show » 37 3.8 No 0
HPGD-008 ENSP00000423066
ENST00000506910
D6RA83
Show all »
Show » Show » 99 10.7 No 0
HPGD-010 ENSP00000423110
ENST00000514584
D6RA66
Show all »
Show » Show » 97 10.5 No 0
HPGD-011 ENSP00000398720
ENST00000422112
P15428
Show all »
Show » Show » 198 21.5 No 0
HPGD-013 ENSP00000296521
ENST00000296521
P15428
Show all »
Show » Show » 178 19.3 No 0
HPGD-201 ENSP00000438017
ENST00000541923
P15428
Show all »
Show » Show » 145 15.7 No 0
HPGD-202 ENSP00000443644
ENST00000542498
P15428
Show all »
Show » Show » 143 15.5 No 0