CMBL

GENE INFORMATION

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Gene name

CMBL (HGNC Symbol)

Synonyms

FLJ23617

Description

Carboxymethylenebutenolidase homolog (Pseudomonas) (HGNC Symbol)

Entrez gene summary

CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]

Chromosome

5

Cytoband

p15.2

Chromosome location (bp)

10275987 - 10308138

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164237 (version 75.37)

Entrez gene

134147

UniProt

Q96DG6 (UniProt - Evidence at protein level)

neXtProt

NX_Q96DG6

Antibodypedia

CMBL antibodies
 

PROTEIN VIEW

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CMBL-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CMBL-001 ENSP00000296658
ENST00000296658
Q96DG6
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