MIOS

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SUBCELL ATLAS - HUMAN

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Summary

Mainly localized to the nucleus but excluded from the nucleoli. In addition localized to the cytoplasm in human cells. Localized to nucleoli,nucleus and cytoplasm in mouse cells.

Main location

Nucleus but not nucleoli

Additional location

Cytoplasm

Reliability

Supportive

Protein evidence

Evidence at protein level

Assay summary

Analysis based on two antibodies, HPA042928 and HPA052223, using immunofluorescence in human and mouse cells
 

 

 

 

 

 

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HPA042928
HPA042928: U-2 OS
HPA042928: U-2 OS
Cell line: U-2 OS
Location: Nucleus but not nucleoli, Cytoplasm
Literature validation: Supportive
HPA042928: A-431
HPA042928: A-431
Cell line: A-431
Location: Nucleus but not nucleoli, Cytoplasm, Cell Junctions
Literature validation: Supportive
HPA042928: U-251 MG
HPA042928: U-251 MG
Cell line: U-251 MG
Location: Nucleus but not nucleoli, Cytoplasm
Literature validation: Supportive
HPA052223
HPA052223: U-2 OS
HPA052223: U-2 OS
Cell line: U-2 OS
Location: Nucleus, Cytoplasm
Literature validation: Supportive
HPA052223: A-431
HPA052223: A-431
Cell line: A-431
Location: Not available
Literature validation: Uncertain
HPA052223 stained U-251 MG
cells unspecifically