SSX5

GENE INFORMATION

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Gene name

SSX5

Synonyms

Description

Synovial sarcoma, X breakpoint 5 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2013]

Chromosome

X

Cytoband

p11.23

Chromosome location (bp)

48045656 - 48056199

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000165583 (version 75.37)

Entrez gene

6758

UniProt

O60225 (UniProt - Evidence at transcript level)

neXtProt

NX_O60225

Antibodypedia

SSX5 antibodies
 

PROTEIN VIEW

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SSX5-001
 
SSX5-002
 
SSX5-003
 
SSX5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SSX5-001 ENSP00000312415
ENST00000311798
O60225
Show all »
Show » Show » 229 26.3 No 0
SSX5-002 ENSP00000366122
ENST00000376923
O60225
Show all »
Show » Show » 188 21.7 No 0
SSX5-003 ENSP00000385051
ENST00000403001
Q5JQ63
Show all »
Show » Show » 128 14.4 No 0
SSX5-201 ENSP00000290558
ENST00000347757
O60225
Show all »
Show » Show » 188 21.7 No 0