ADAMTS15

TISSUE ATLAS

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Gene description

ADAM metallopeptidase with thrombospondin type 1 motif, 15

RNA tissue category

Tissue enhanced (adipose tissue).

Protein summary

Detected at High or Medium expression level in 50 of 80 analyzed normal tissue cell types.

Protein expression

Normal tissues displayed moderate cytoplasmic positivity with additional membranous staining i nseveral cases. Strong staining was observed in adrenocortical cells, stomach, small intestine, gall bladder, salivary gland and smooth muscle cells. Glandular cells of cervix, endometrial stroma, non germinal center cells and most of the squamous epithelia were weakly stained or negative.

Protein class

Enzymes, Predicted secreted proteins

Predicted localization

Secreted

Protein evidence

Evidence at transcript level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis N/A
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA042867