CASC4

GENE INFORMATION

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Gene name

CASC4 (HGNC Symbol)

Synonyms

DKFZp459F1927, H63

Description

Cancer susceptibility candidate 4 (HGNC Symbol)

Entrez gene summary

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]

Chromosome

15

Cytoband

q15.3

Chromosome location (bp)

44580927 - 44707956

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166734 (version 75.37)

Entrez gene

113201

UniProt

Q6P4E1 (UniProt - Evidence at protein level)

neXtProt

NX_Q6P4E1

Antibodypedia

CASC4 antibodies
 

PROTEIN VIEW

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CASC4-001
 
CASC4-002
 
CASC4-005
 
CASC4-006
 
CASC4-007
 
CASC4-009
 
CASC4-011
 
CASC4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CASC4-001 ENSP00000299957
ENST00000299957
Q6P4E1
Show all »
Show » Show » 436 49.5 No 0
CASC4-002 ENSP00000335063
ENST00000345795
Q6P4E1
Show all »
Show » Show » 380 43.3 No 0
CASC4-005 ENSP00000453720
ENST00000557945
Q6P4E1
Show all »
Show » Show » 177 20.9 No 0
CASC4-006 ENSP00000453703
ENST00000559222
H0YMR0
Show all »
Show » 113 13.5 No 0
CASC4-007 ENSP00000453850
ENST00000558735
Show » 82 8.4 No 0
CASC4-009 ENSP00000453465
ENST00000558847
Show » 161 17.8 No 0
CASC4-011 ENSP00000452833
ENST00000561305
H0YKJ7
Show all »
Show » 24 2.9 No 0
CASC4-201 ENSP00000354067
ENST00000360824
Q6P4E1
Show all »
Show » Show » 177 20.9 No 0