TAC3

GENE INFORMATION

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Gene name

TAC3 (HGNC Symbol)

Synonyms

NKB, NKNB, ZNEUROK1

Description

Tachykinin 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Chromosome

12

Cytoband

q13.3

Chromosome location (bp)

57403784 - 57422667

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166863 (version 75.37)

Entrez gene

6866

UniProt

Q9UHF0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHF0

Antibodypedia

TAC3 antibodies
 

PROTEIN VIEW

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TAC3-001
 
TAC3-002
 
TAC3-003
 
TAC3-004
 
TAC3-005
 
TAC3-006
 
TAC3-007
 
TAC3-008
 
TAC3-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TAC3-001 ENSP00000404056
ENST00000458521
Q9UHF0
Show all »
Show » Show » 121 13.4 Yes 0
TAC3-002 ENSP00000350236
ENST00000357616
Q9UHF0
Show all »
Show » Show » 135 14.8 Yes 0
TAC3-003 ENSP00000408131
ENST00000438756
Q9UHF0
Show all »
Show » Show » 135 14.8 Yes 0
TAC3-004 ENSP00000377445
ENST00000393867
Q9UHF0
Show all »
Show » Show » 135 14.8 Yes 0
TAC3-005 ENSP00000368721
ENST00000379411
Q9UHF0
Show all »
Show » Show » 103 11.4 Yes 0
TAC3-006 ENSP00000408208
ENST00000441881
Q9UHF0
Show all »
Show » Show » 103 11.4 Yes 0
TAC3-007 ENSP00000416292
ENST00000423597
Q9UHF0
Show all »
Show » Show » 103 11.4 Yes 0
TAC3-008 ENSP00000300108
ENST00000300108
Q9UHF0
Show all »
Show » Show » 121 13.4 Yes 0
TAC3-010 ENSP00000402995
ENST00000415231
Q9UHF0
Show all »
Show » Show » 121 13.4 Yes 0