PPP2R3B

GENE INFORMATION

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Gene name

PPP2R3B (HGNC Symbol)

Synonyms

PPP2R3L, PPP2R3LY, PR48

Description

Protein phosphatase 2, regulatory subunit B'', beta (HGNC Symbol)

Entrez gene summary

Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010]

Chromosome

X

Cytoband

p22.33

Chromosome location (bp)

294698 - 347690

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167393 (version 75.37)

Entrez gene

28227

UniProt

Q9Y5P8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5P8

Antibodypedia

PPP2R3B antibodies
 

PROTEIN VIEW

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PPP2R3B-001
 
PPP2R3B-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP2R3B-001 ENSP00000375080
ENST00000390665
Q9Y5P8
Show all »
Show » Show » 575 65.1 No 0
PPP2R3B-002 ENSP00000371038
ENST00000381625
C9JMU6
Show all »
Show » 169 18.8 No 0