TPM4

GENE INFORMATION

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Gene name

TPM4

Synonyms

Description

Tropomyosin 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

16177831 - 16213813

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167460 (version 75.37)

Entrez gene

7171

UniProt

P67936 (UniProt - Evidence at protein level)

neXtProt

NX_P67936

Antibodypedia

TPM4 antibodies
 

PROTEIN VIEW

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 « 
 
TPM4-001
 
TPM4-002
 
TPM4-007
 
TPM4-008
 
TPM4-009
 
TPM4-010
 
TPM4-012
 
TPM4-014
 
TPM4-015
 
TPM4-016
 
TPM4-019
 
TPM4-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TPM4-001 ENSP00000345230
ENST00000344824
P67936
Show all »
Show » Show » 284 32.7 No 0
TPM4-002 ENSP00000300933
ENST00000300933
P67936
Show all »
Show » Show » 248 28.5 No 0
TPM4-007 ENSP00000466158
ENST00000589897
K7ELP0
Show all »
Show » Show » 69 8 No 0
TPM4-008 ENSP00000468246
ENST00000586499
K7ERG3
Show all »
Show » 170 19.3 No 0
TPM4-009 ENSP00000467087
ENST00000586833
K7ENT6
Show all »
Show » 179 20.6 No 0
TPM4-010 ENSP00000467558
ENST00000588507
K7EPV9
Show all »
Show » Show » 96 11.3 No 0
TPM4-012 ENSP00000467250
ENST00000588410
K7EP68
Show all »
Show » 138 15.8 No 0
TPM4-014 ENSP00000466106
ENST00000588483
Show » 16 2 No 0
TPM4-015 ENSP00000466654
ENST00000592138
K7EMU5
Show all »
Show » Show » 102 12 No 0
TPM4-016 ENSP00000467319
ENST00000588032
Show » 110 12.5 No 0
TPM4-019 ENSP00000468010
ENST00000592822
K7EQW8
Show all »
Show » 59 6.8 No 0
TPM4-201 ENSP00000439135
ENST00000538887
P67936
Show all »
Show » Show » 284 32.7 No 0