KLK5

GENE INFORMATION

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Gene name

KLK5 (HGNC Symbol)

Synonyms

KLK-L2, SCTE

Description

Kallikrein-related peptidase 5 (HGNC Symbol)

Entrez gene summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.41

Chromosome location (bp)

51446559 - 51456349

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167754 (version 75.37)

Entrez gene

25818

UniProt

Q9Y337 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y337

Antibodypedia

KLK5 antibodies
 

PROTEIN VIEW

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KLK5-001
 
KLK5-004
 
KLK5-005
 
KLK5-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLK5-001 ENSP00000337733
ENST00000336334
Q9Y337
Show all »
Show » Show » 293 32 Yes 0
KLK5-004 ENSP00000471966
ENST00000593428
Q9Y337
Show all »
Show » Show » 293 32 Yes 0
KLK5-005 ENSP00000375685
ENST00000391809
Q9Y337
Show all »
Show » Show » 293 32 Yes 0
KLK5-006 ENSP00000469439
ENST00000594846
M0QXX2
Show all »
Show » Show » 205 22.4 Yes 0