SOAT2

GENE INFORMATION

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Gene name

SOAT2 (HGNC Symbol)

Synonyms

ACAT2

Description

Sterol O-acyltransferase 2 (HGNC Symbol)

Entrez gene summary

Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

53497302 - 53518322

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167780 (version 75.37)

Entrez gene

8435

UniProt

O75908 (UniProt - Evidence at transcript level)

neXtProt

NX_O75908

Antibodypedia

SOAT2 antibodies
 

PROTEIN VIEW

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SOAT2-001
 
SOAT2-002
 
SOAT2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SOAT2-001 ENSP00000301466
ENST00000301466
O75908
Show all »
Show » Show » 522 59.9 No 7
SOAT2-002 ENSP00000442234
ENST00000542365
F5H7W4
Show all »
Show » Show » 310 34.9 No 3
SOAT2-003 ENSP00000450120
ENST00000551896
F8VPE9
Show all »
Show » Show » 170 19.3 No 2