VPREB1

GENE INFORMATION

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Gene name

VPREB1 (HGNC Symbol)

Synonyms

CD179A, VpreB

Description

Pre-B lymphocyte 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Chromosome

22

Cytoband

q11.22

Chromosome location (bp)

22599087 - 22599927

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169575 (version 75.37)

Entrez gene

7441

UniProt

P12018 (UniProt - Evidence at protein level)

neXtProt

NX_P12018

Antibodypedia

VPREB1 antibodies
 

PROTEIN VIEW

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VPREB1-001
 
VPREB1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VPREB1-001 ENSP00000385361
ENST00000403807
P12018
Show all »
Show » Show » 145 16.6 Yes 0
VPREB1-002 ENSP00000304590
ENST00000302273
F8W8C9
Show all »
Show » Show » 144 16.3 Yes 0