HOXD12

TISSUE ATLAS

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Gene description

Homeobox D12

RNA tissue category

Tissue enhanced (colon).

Protein summary

Detected at High or Medium expression level in 25 of 79 analyzed normal tissue cell types.

Protein expression

Gastrointestinal tract, squamous epithelia, urothelium, epididymis and gall bladder showed moderate to strong cytoplasmic and membranous positivity. Salivary gland, hepatocytes, exocrine pancreas, seminiferus ducts and uterine glands exhibited moderate cytoplasmic and nuclear staining whereas subset of renal tubules showed strong staining. Breast glandular cells and prostate displayed moderate cytoplasmic staining. Remaining normal tissues were weakly stained or negative.

Protein class

Transcription factors

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Endometrium 2
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

20
10
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus N/A
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA059444