KRT4

GENE INFORMATION

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Gene name

KRT4 (HGNC Symbol)

Synonyms

CK4, CYK4, K4

Description

Keratin 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

53200333 - 53208335

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170477 (version 75.37)

Entrez gene

3851

UniProt

P19013 (UniProt - Evidence at protein level)

neXtProt

NX_P19013

Antibodypedia

KRT4 antibodies
 

PROTEIN VIEW

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KRT4-001
 
KRT4-002
 
KRT4-003
 
KRT4-201
 
KRT4-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KRT4-001 ENSP00000448220
ENST00000551956
P19013
Show all »
Show » Show » 520 56.1 No 0
KRT4-002 ENSP00000449755
ENST00000548097
F8VX05
Show all »
Show » 78 7.8 No 0
KRT4-003 ENSP00000447320
ENST00000552668
F8VZR6
Show all »
Show » 86 8.7 No 0
KRT4-201 ENSP00000293774
ENST00000293774
P19013
Show all »
Show » Show » 594 63.9 No 0
KRT4-202 ENSP00000387904
ENST00000458244
F5H8K9
Show all »
Show » Show » 500 54 No 0