CDCA4

GENE INFORMATION

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Gene name

CDCA4 (HGNC Symbol)

Synonyms

FLJ20764, Hepp

Description

Cell division cycle associated 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]

Chromosome

14

Cytoband

q32.33

Chromosome location (bp)

105475910 - 105487485

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170779 (version 75.37)

Entrez gene

55038

UniProt

Q9BXL8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXL8

Antibodypedia

CDCA4 antibodies
 

PROTEIN VIEW

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CDCA4-001
 
CDCA4-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDCA4-001 ENSP00000337226
ENST00000336219
Q9BXL8
Show all »
Show » Show » 241 26.1 No 0
CDCA4-002 ENSP00000376369
ENST00000392590
Q9BXL8
Show all »
Show » Show » 241 26.1 No 0