TRH

GENE INFORMATION

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Gene name

TRH

Synonyms

Description

Thyrotropin-releasing hormone (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]

Chromosome

3

Cytoband

q22.1

Chromosome location (bp)

129693148 - 129696781

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170893 (version 75.37)

Entrez gene

7200

UniProt

P20396 (UniProt - Evidence at protein level)

neXtProt

NX_P20396

Antibodypedia

TRH antibodies
 

PROTEIN VIEW

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TRH-001
 
TRH-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRH-001 ENSP00000303452
ENST00000302649
P20396
Show all »
Show » Show » 242 27.4 Yes 0
TRH-002 ENSP00000426522
ENST00000507066
D6RFM1
Show all »
Show » Show » 238 27 Yes 0