FUT3

TISSUE ATLAS

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Gene description

Fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)

RNA tissue category

Tissue enhanced (colon, esophagus).

Protein summary

Detected at High or Medium expression level in 17 of 77 analyzed normal tissue cell types.

Protein expression

Normal tissues displayed weak to moderate cytoplasmic staining with additional nuclear positivity in small intestine, Purkinje cells, squamous epithelia and testis. Membranous staining was observed in stomach, bronchus and glandular cells of uterus. Small intestine and cells in granular layer of cerebellum exhibited strong immunoreactivity. Adrenocortical cells, hematopoietic tissue, breast, glial cells, liver, prostate and most of the lymphoid tissue were negative. Caution: Based on antibody targeting proteins from multiple genes.

Protein class

Blood group antigen proteins, Enzymes, Predicted membrane proteins

Predicted localization

Membrane

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA046966

Other gene match

HPA046966 FUT5 - ENSG00000130383 [97%]
FUT6 - ENSG00000156413 [100%]