CHST11

GENE INFORMATION

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Gene name

CHST11 (HGNC Symbol)

Synonyms

C4ST, C4St-1, C4ST1, HSA269537

Description

Carbohydrate (chondroitin 4) sulfotransferase 11 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Chromosome

12

Cytoband

q23.3

Chromosome location (bp)

104849073 - 105155792

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171310 (version 75.37)

Entrez gene

50515

UniProt

Q9NPF2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPF2

Antibodypedia

CHST11 antibodies
 

PROTEIN VIEW

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CHST11-001
 
CHST11-002
 
CHST11-005
 
CHST11-006
 
CHST11-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHST11-001 ENSP00000305725
ENST00000303694
Q9NPF2
Show all »
Show » Show » 352 41.6 Yes 0
CHST11-002 ENSP00000450004
ENST00000549260
Q9NPF2
Show all »
Show » Show » 347 41 No 0
CHST11-005 ENSP00000449095
ENST00000549016
F8VXK3
Show all »
Show » Show » 158 18.5 No 0
CHST11-006 ENSP00000448678
ENST00000546689
F8VRG6
Show all »
Show » 72 8.4 No 0
CHST11-007 ENSP00000449093
ENST00000547956
F8VXK7
Show all »
Show » 77 8.9 Yes 0