NAT1

GENE INFORMATION

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Gene name

NAT1 (HGNC Symbol)

Synonyms

AAC1

Description

N-acetyltransferase 1 (arylamine N-acetyltransferase) (HGNC Symbol)

Entrez gene summary

This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Chromosome

8

Cytoband

p22

Chromosome location (bp)

18027986 - 18081198

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000171428 (version 75.37)

Entrez gene

9

UniProt

P18440 (UniProt - Evidence at protein level)

neXtProt

NX_P18440

Antibodypedia

NAT1 antibodies
 

PROTEIN VIEW

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NAT1-001
 
NAT1-002
 
NAT1-003
 
NAT1-007
 
NAT1-201
 
NAT1-202
 
NAT1-203
 
NAT1-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NAT1-001 ENSP00000307218
ENST00000307719
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-002 ENSP00000428270
ENST00000518029
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-003 ENSP00000429407
ENST00000517492
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-007 ENSP00000429341
ENST00000520546
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-201 ENSP00000444609
ENST00000535084
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-202 ENSP00000440434
ENST00000539092
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-203 ENSP00000440900
ENST00000541942
P18440
Show all »
Show » Show » 290 33.9 No 0
NAT1-204 ENSP00000443194
ENST00000545197
F5H5R8
Show all »
Show » Show » 352 40.8 No 0