CLEC12A

GENE INFORMATION

? »

Gene name

CLEC12A (HGNC Symbol)

Synonyms

CLL-1, MICL

Description

C-type lectin domain family 12, member A (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]

Chromosome

12

Cytoband

p13.2

Chromosome location (bp)

10103915 - 10148293

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172322 (version 75.37)

Entrez gene

160364

UniProt

Q5QGZ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q5QGZ9

Antibodypedia

CLEC12A antibodies
 

PROTEIN VIEW

? »
 
 
 
CLEC12A-001
 
CLEC12A-002
 
CLEC12A-003
 
CLEC12A-006
 
CLEC12A-007
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLEC12A-001 ENSP00000302804
ENST00000304361
Q5QGZ9
Show all »
Show » Show » 265 30.8 No 1
CLEC12A-002 ENSP00000405244
ENST00000434319
Q5QGZ9
Show all »
Show » Show » 213 24.4 No 1
CLEC12A-003 ENSP00000345448
ENST00000350667
Q5QGZ9
Show all »
Show » Show » 232 27.3 No 0
CLEC12A-006 ENSP00000379764
ENST00000396507
A8MVL9
Show all »
Show » 165 19 No 1
CLEC12A-007 ENSP00000347916
ENST00000355690
Q5QGZ9
Show all »
Show » Show » 275 32 No 1