PRSS27

TISSUE ATLAS

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Gene description

Protease, serine 27

RNA tissue category

Group enriched (esophagus, tonsil).

Protein summary

Detected at High or Medium expression level in 25 of 82 analyzed normal tissue cell types.

Protein expression

Most normal cells showed weak to moderate cytoplasmic positivity. Strong staining was observed in exocrine pancreas, small intestine, Langerhans cells in skin and the superficial layers in non-keratinized squamous epithelium. Pancreatic islets, lymphoid tissue and most cells in the female genitalia were negative.

Protein class

Enzymes, Predicted secreted proteins

Predicted localization

Secreted

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Esophagus
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

200
100
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

CAB024920