CES3

GENE INFORMATION

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Gene name

CES3 (HGNC Symbol)

Synonyms

ES31, FLJ21736

Description

Carboxylesterase 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.[provided by RefSeq, Jun 2010]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

66995140 - 67009051

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172828 (version 75.37)

Entrez gene

23491

UniProt

Q6UWW8 (UniProt - Evidence at protein level)

neXtProt

NX_Q6UWW8

Antibodypedia

CES3 antibodies
 

PROTEIN VIEW

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CES3-001
 
CES3-002
 
CES3-003
 
CES3-004
 
CES3-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CES3-001 ENSP00000304782
ENST00000303334
Q6UWW8
Show all »
Show » Show » 571 62.3 Yes 0
CES3-002 ENSP00000377602
ENST00000394037
Q6UWW8
Show all »
Show » Show » 568 62 Yes 0
CES3-003 ENSP00000445559
ENST00000543856
Q6UWW8
Show all »
Show » Show » 210 24.1 No 0
CES3-004 ENSP00000457547
ENST00000570236
H3BUA3
Show all »
Show » Show » 379 40.1 Yes 0
CES3-008 ENSP00000456203
ENST00000566453
H3BRE5
Show all »
Show » 40 4.2 Yes 0