CYSLTR1

TISSUE ATLAS

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Gene description

Cysteinyl leukotriene receptor 1

RNA tissue category

Mixed.

Protein summary

Detected at High or Medium expression level in 8 of 80 analyzed normal tissue cell types.

Protein expression

Distinct cytoplasmic positivity with a granular pattern was observed in macrophages and granulocytes. Basal cell layer of squamous epithelia, glandular cells in gastrointestinal tract, subsets of cells in red pulp of spleen and renal tubules showed moderate cytoplasmic positivity with a granular pattern. Nucleolar staining was observed in fractions of cells in CNS. Other normal tissues were in general negative.

Protein class

FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters

Predicted localization

Membrane

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Spleen
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

20
10
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA010546