ERCC4

GENE INFORMATION

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Gene name

ERCC4 (HGNC Symbol)

Synonyms

FANCQ, RAD1, XPF

Description

Excision repair cross-complementing rodent repair deficiency, complementation group 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009]

Chromosome

16

Cytoband

p13.12

Chromosome location (bp)

14014014 - 14046202

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175595 (version 75.37)

Entrez gene

2072

UniProt

Q92889 (UniProt - Evidence at protein level)

neXtProt

NX_Q92889

Antibodypedia

ERCC4 antibodies
 

PROTEIN VIEW

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ERCC4-001
 
ERCC4-002
 
ERCC4-003
 
ERCC4-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ERCC4-001 ENSP00000310520
ENST00000311895
Q92889
Show all »
Show » Show » 916 104.5 No 0
ERCC4-002 ENSP00000461322
ENST00000462862
I3L4K0
Show all »
Show » 35 4.2 No 0
ERCC4-003 ENSP00000459933
ENST00000575156
A5PKV6
Show all »
Show » 372 42.7 No 0
ERCC4-007 ENSP00000461883
ENST00000574194
Show » 75 9 No 0