GPX2

GENE INFORMATION

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Gene name

GPX2 (HGNC Symbol)

Synonyms

GSHPX-GI

Description

Glutathione peroxidase 2 (gastrointestinal) (HGNC Symbol)

Entrez gene summary

This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. The protein encoded by this locus contains a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]

Chromosome

14

Cytoband

q23.3

Chromosome location (bp)

65405870 - 65409531

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000176153 (version 75.37)

Entrez gene

2877

UniProt

P18283 (UniProt - Evidence at protein level)

neXtProt

NX_P18283

Antibodypedia

GPX2 antibodies
 

PROTEIN VIEW

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GPX2-001
 
GPX2-002
 
GPX2-003
 
GPX2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPX2-001 ENSP00000374265
ENST00000389614
P18283
Show all »
Show » Show » 190 22 No 0
GPX2-002 ENSP00000450991
ENST00000553522
Show » Show » 78 8.8 No 0
GPX2-003 ENSP00000451844
ENST00000557323
Show » Show » 78 9 No 0
GPX2-004 ENSP00000451721
ENST00000557049
H0YJK8
Show all »
Show » Show » 134 15.5 No 0