SLC25A22

TISSUE ATLAS

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Gene description

Solute carrier family 25 (mitochondrial carrier: glutamate), member 22

RNA tissue category

Tissue enhanced (cerebral cortex).

Protein summary

Detected at High or Medium expression level in 36 of 81 analyzed normal tissue cell types.

Protein expression

Most of the normal tissues displayed moderate cytoplasmic positivity. Additional nuclear staining was observed in a few cases. Strong staining was observed in exocrine pancreas, prostate glands, neuronal cells and a fraction of cells in seminiferous ducts. Bile ducts, lymphoid tissues and muscle cells were generally negative.

Protein class

Disease related genes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters

Predicted localization

Membrane

Protein evidence

Evidence at protein level

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Prostate
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA014662