FOXE1

GENE INFORMATION

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Gene name

FOXE1 (HGNC Symbol)

Synonyms

FKHL15, FOXE2, HFKH4, TITF2, TTF-2

Description

Forkhead box E1 (thyroid transcription factor 2) (HGNC Symbol)

Entrez gene summary

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q22.33

Chromosome location (bp)

100615536 - 100618986

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000178919 (version 75.37)

Entrez gene

2304

UniProt

O00358 (UniProt - Evidence at protein level)

neXtProt

NX_O00358

Antibodypedia

FOXE1 antibodies
 

PROTEIN VIEW

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FOXE1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXE1-001 ENSP00000364265
ENST00000375123
O00358
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