APOBEC3B

GENE INFORMATION

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Gene name

APOBEC3B (HGNC Symbol)

Synonyms

FLJ21201, PHRBNL

Description

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B (HGNC Symbol)

Entrez gene summary

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

Chromosome

22

Cytoband

q13.1

Chromosome location (bp)

39378352 - 39388809

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000179750 (version 75.37)

Entrez gene

9582

UniProt

Q9UH17 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UH17

Antibodypedia

APOBEC3B antibodies
 

PROTEIN VIEW

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APOBEC3B-001
 
APOBEC3B-002
 
APOBEC3B-003
 
APOBEC3B-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOBEC3B-001 ENSP00000327459
ENST00000333467
Q9UH17
Show all »
Show » Show » 382 45.9 No 0
APOBEC3B-002 ENSP00000385060
ENST00000402182
B0QYD3
Show all »
Show » Show » 490 57.2 No 0
APOBEC3B-003 ENSP00000385068
ENST00000407298
Q9UH17
Show all »
Show » Show » 357 43.1 No 0
APOBEC3B-005 ENSP00000338897
ENST00000335760
Q9UH17
Show all »
Show » Show » 251 29.8 No 0